Conventional Practice for Medical Conditions for Chronic Opioid Therapy

Conventional practice for medical conditions for chronic opioid therapy.

When considering chronic opioid therapy (COT) for chronic noncancer pain, it has been proposed that it is prudent to contemplate 4 questions which may be useful and influence medical decision making (1): 1. What is the conventional practice? 2. Are there reasonable alternatives to COT? 3. What is the risk of adverse events? 4. Is the patient likely to be a responsible drug-taker? Question 4 – (...

Opioid therapy for chronic pain.

N Engl J Med 2003;349:1943-53. Copyright © 2003 Massachusetts Medical Society. pium is a bitter, brown, granular powder derived from the seedpod of the poppy ( Papaver somniferum ). People have used opium for the relief of pain and suffering for thousands of years. Before the 19th century, opium was cultivated and used chiefly in the Middle East, whereas in Europe and the United States it was a...

Long-Term Opioid Therapy for Chronic Pain.

Opioid dependence and substitution therapy: thymoquinone as potential novel supplement therapy for better outcome for methadone maintenance therapy substitution therapy

Methadone is widely being used for opioid substitution therapy. However, the administration of methadone to opioid dependent individual is frequently accompanied by withdrawal syndrome and chemical dependency develops. Other than that, it is also difficult to retain patients in the treatment programme making their retention rates are decreasing over time. This article is written to higlights th...

Tapering Long-term Opioid Therapy in Chronic Noncancer Pain: Evidence and Recommendations for Everyday Practice.

Increasing concern about the risks and limited evidence supporting the therapeutic benefit of long-term opioid therapy for chronic noncancer pain are leading prescribers to consider discontinuing the use of opioids. In addition to overt addiction or diversion, the presence of adverse effects, diminishing analgesia, reduced function and quality of life, or the absence of progress toward function...